Yonsei Medical Journal - Volume 53, issue 3

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Electronic ISSN
1976-2437
Print ISSN
0513-5796

Abstract

Purpose

Tubulointerstitial hypoxia in the kidney is considered a hallmark of injury and a mediator of the progression of tubulointerstitial fibrosis. Hypoxia-inducible factor-1alpha (HIF-1alpha), a master transcription factor in cellular adaptation to hypoxia, regulates a wide variety of genes, so

Journal: Yonsei Medical Journal, vol. 53, no. 3, 2012