The Journal of Experimental Medicine - Volume 206, issue 5

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), are dependent on constitutive activation of nuclear factor κB (NF-κB). NF-κB activation through various stimuli is negatively regulated by the zinc finger protein A20. To

Journal: The Journal of Experimental Medicine, vol. 206, no. 5, 2009