The Journal of Experimental Medicine - Volume 204, issue 4

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

Natural killer (NK) cells are sentinel components of the innate response to pathogens, but the cell types, pathogen recognition receptors, and cytokines required for their activation in vivo are poorly defined. Here, we investigated the role of plasmacytoid dendritic cells (pDCs), myeloid DCs (mD

Journal: The Journal of Experimental Medicine, vol. 204, no. 4, 2007

Abstract

The increasing complexity of biomedical research is leading to the exploration of new models for large-scale collaborative research. This Big Science approach, however, has created anxieties and potential tensions between investigator-driven research, and research guided by a more organized, coll

Journal: The Journal of Experimental Medicine, vol. 204, no. 4, 2007