The Journal of Experimental Medicine - Volume 203, issue 7

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

T cells need to be activated by dendritic cells (DCs) before they will attack a tumor. Sumimoto et al. (page 1651) now show that a common skin cancer mutation interferes with this pathway, thus helping the tumor to evade the body's immune defenses.

Activating point mutations in the serine-t

Journal: The Journal of Experimental Medicine, vol. 203, no. 7, 2006