The Journal of Experimental Medicine - Volume 199, issue 8

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

PML–RARA was proposed to initiate acute promyelocytic leukemia (APL) through PML–RARA homodimer–triggered repression. Here, we examined the nature of the PML–RARA protein complex and of its DNA targets in APL cells. Using a selection/amplification approach, we demonstrate that PML–RARA tar

Journal: The Journal of Experimental Medicine, vol. 199, no. 8, 2004