The Journal of Experimental Medicine - Volume 188, issue 7

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8+ T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance. Here, we demonstrate that phagocytosis of

Journal: The Journal of Experimental Medicine, vol. 188, no. 7, 1998