The Journal of Experimental Medicine - Volume 185, issue 4

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

The genetic origins of CD8+ T cell–recognized unique antigens to which mice respond when immunized with syngeneic tumor cells are unknown. The ultraviolet light-induced murine tumor 8101 expresses an H-2Kb-restricted immunodominant antigen, A, that induces cytolytic CD8

Journal: The Journal of Experimental Medicine, vol. 185, no. 4, 1997

Abstract

Monoclonal antibodies (mAbs) to the polysaccharide capsule of Cryptococcus neoformans can prolong survival in mice. However, the properties of antibodies that mediate protection are not fully understood. The IgM mAbs 12A1 and 13F1 originated from the same B cell and differ only by somati

Journal: The Journal of Experimental Medicine, vol. 185, no. 4, 1997