The Journal of Experimental Medicine - Volume 183, issue 5

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

Tyrosinase was the first melanoma-associated antigen shown to be recognized by CD4+ T cells. In this study, we have identified two HLA- DRB1*0401-restricted peptides recognized by these T cells: Ty 56-70 and Ty 448-462. As with many of the MHC class I-restricted melanoma epitopes, both are nonmut

Journal: The Journal of Experimental Medicine, vol. 183, no. 5, 1996