The Journal of Experimental Medicine - Volume 179, issue 1

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

The previous paper in this series demonstrates that rat T cells developing de novo in the presence of mouse mammary tumor virus (Mtv) antigens in rat-->severe combined immunodeficiency (SCID) mouse xenochimeras display a distinct pattern of V beta-restricted deletion; this deletion pattern is

Journal: The Journal of Experimental Medicine, vol. 179, no. 1, 1994

Abstract

A major obstacle to the effective use of adoptive immunotherapeutic treatment of cancer is the difficulty of obtaining tumor-reactive lymphocytes in either sufficient numbers or with appropriate in vivo function to make such an approach feasible. Previous studies have shown that antitumor cytotox

Journal: The Journal of Experimental Medicine, vol. 179, no. 1, 1994