The Journal of Experimental Medicine - Volume 157, issue 3

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

A synthetic 23-amino acid peptide derived from the CH3 domain of human IgG1 was found to be a potent adjuvant as well as a polyclonal activator. The Fc peptide was found to enhance human and murine humoral, and T cell-mediated immune responses. Moreover, in vivo administration of Fc peptide enhan

Journal: The Journal of Experimental Medicine, vol. 157, no. 3, 1983

Abstract

The ability of monoclonal antibodies against the Thy-1.1 differentiation antigen to inhibit the growth of transplanted syngeneic AKR/J SL2 leukemic cells has been previously demonstrated. In the present study we further examined therapy with monoclonal antibody of the IgG2a isotype, which was the

Journal: The Journal of Experimental Medicine, vol. 157, no. 3, 1983