The Journal of Experimental Medicine - Volume 146, issue 6

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Electronic ISSN
1540-9538
Print ISSN
0022-1007

Abstract

During ontogeny IgD appears later than IgM on splenocytes of neonatal mice (1) and at a time when mice develop a markedly increased immune responsiveness (2). Based on these observations, it was suggested that IgD serves as a “triggering” isotype for induction of immune responses, whereas surface

Journal: The Journal of Experimental Medicine, vol. 146, no. 6, 1977

Abstract

Lipoproteins, isolated by sequential flotation at densities 1.006, 1.019, 1.063, and 1.21, were examined for their ability to inhibit human lymphocytes stimulated by allogeneic cells and by lectins (phytohemagglutinin-P and concanavalin A). All the classes of normal plasma lipoproteins inhibited

Journal: The Journal of Experimental Medicine, vol. 146, no. 6, 1977