The Journal of Cell Biology - Volume 183, issue 5

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

When starved of their food source and then presented with a chemoattractant signal like cAMP, individual Dictyostelium cells acquire a polarized morphology and aggregate to form a migrating stream. This is the first step in a developmental program that culminates in the formation of a mult

Journal: The Journal of Cell Biology, vol. 183, no. 5, 2008

Abstract

Claudin family proteins form the physical barriers of tight junctions (TJs) and regulate paracellular diffusion across polarized epithelia. In addition to these heterotypic TJs, claudin 11 forms autotypic TJs comprising the radial component of central nervous system myelin. The exact function of

Journal: The Journal of Cell Biology, vol. 183, no. 5, 2008