The Journal of Cell Biology - Volume 180, issue 3

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

RNA-binding proteins of the L7Ae family are at the heart of many essential ribonucleoproteins (RNPs), including box C/D and H/ACA small nucleolar RNPs, U4 small nuclear RNP, telomerase, and messenger RNPs coding for selenoproteins. In this study, we show that Nufip and its yeast homologue Rsa1 ar

Journal: The Journal of Cell Biology, vol. 180, no. 3, 2008

Abstract

The mitotic checkpoint is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. Mitotic checkpoint function depends on numerous kinetochore proteins, including ZW10, ROD, and Zwilch (the ROD–ZW10–Zwilch complex). Through an extensive mutagenesis scr

Journal: The Journal of Cell Biology, vol. 180, no. 3, 2008