The Journal of Cell Biology - Volume 177, issue 4

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

The first microRNA (miRNA) knockout mice reveal that these tiny RNAs have sizeable power over mammalian physiology, as shown by three new reports.

Germinal centers (brown) are abnormal in mice lacking miR-155 (bottom).

RAJEWSKY/AAAS

Rather than coding for proteins, miRNAs decrea

Journal: The Journal of Cell Biology, vol. 177, no. 4, 2007