The Journal of Cell Biology - Volume 169, issue 4

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Polarized exocytosis plays a major role in development and cell differentiation but the mechanisms that target exocytosis to specific membrane domains in animal cells are still poorly understood. We characterized Drosophila Sec6, a component of the exocyst complex that is believed to tethe

Journal: The Journal of Cell Biology, vol. 169, no. 4, 2005

Abstract

Many progenitor cell types start differentiation by turning on transcription. But on page 577, Shen et al. show that oligodendrocytes (OLs)—the myelin-forming cells of the nervous system—require a general transcriptional shutdown for differentiation.The transcriptional slowing is due to histone d

Journal: The Journal of Cell Biology, vol. 169, no. 4, 2005