The Journal of Cell Biology - Volume 165, issue 2

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Secretory vesicles wishing to play follow-the-leader use a particular SNARE to show them where the leader went, as shown by Takahashi et al. on page 255.

Figure

SNAP25 (red) moves into the bulge (outlined) where sequential exocytosis is taking place (left to right).

SNAP25 (red

Journal: The Journal of Cell Biology, vol. 165, no. 2, 2004

Abstract

An active mechanism keeps vesicles that are departing the ER from turning round and fusing back to it, say Faustin Kamena and Anne Spang (Max Planck, Tübingen, Germany).

Figure

Only the tip20-8 mutant allows a protein to double-back to the ER for trimming.

Spang/AAAS

Journal: The Journal of Cell Biology, vol. 165, no. 2, 2004