The Journal of Cell Biology - Volume 161, issue 2

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Actin filament pointed-end dynamics are thought to play a critical role in cell motility, yet regulation of this process remains poorly understood. We describe here a previously uncharacterized tropomodulin (Tmod) isoform, Tmod3, which is widely expressed in human tissues and is present in human

Journal: The Journal of Cell Biology, vol. 161, no. 2, 2003

Abstract

Infection with the human microbial pathogen Helicobacter pylori is assumed to lead to invasive gastric cancer. We find that H. pylori activates the hepatocyte growth factor/scatter factor receptor c-Met, which is involved in invasive growth of tumor cells. The H. pylori effec

Journal: The Journal of Cell Biology, vol. 161, no. 2, 2003

Abstract

The Aurora B kinase complex is a critical regulator of chromosome segregation and cytokinesis. In Caenorhabditis elegans, AIR-2 (Aurora B) function requires ICP-1 (Incenp) and BIR-1 (Survivin). In various systems, Aurora B binds to orthologues of these proteins. Through genetic analysis, w

Journal: The Journal of Cell Biology, vol. 161, no. 2, 2003