The Journal of Cell Biology - Volume 159, issue 6

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Mechanisms for activating the actin-related protein 2/3 (Arp2/3) complex have been the focus of many recent studies. Here, we identify a novel mode of Arp2/3 complex regulation mediated by the highly conserved actin binding protein coronin. Yeast coronin (Crn1) physically associates with the Arp2

Journal: The Journal of Cell Biology, vol. 159, no. 6, 2002

Abstract

eW have used electron microscopy and single-particle image processing to study head conformation in myosin V molecules. We find that in the presence of ATP, many heads have a sharply angled conformation that is rare in its absence. The sharply angled conformation is similar to a myosin II atomic

Journal: The Journal of Cell Biology, vol. 159, no. 6, 2002