The Journal of Cell Biology - Volume 159, issue 5

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

CVaspase activation is a key event in apoptosis execution. In stress-induced apoptosis, the mitochondrial pathway of caspase activation is believed to be of central importance. In this pathway, cytochrome c released from mitochondria facilitates the formation of an Apaf-1 apoptosome that recruits

Journal: The Journal of Cell Biology, vol. 159, no. 5, 2002

Abstract

Two recent studies in mammalian cells have shown that spindle checkpoint proteins can be found at the nuclear pore during interphase and that nucleoporins localize to kinetochores during mitosis. A new study on page 807 by Iouk et al. provides the first functional connection between kinetochores

Journal: The Journal of Cell Biology, vol. 159, no. 5, 2002