The Journal of Cell Biology - Volume 158, issue 3

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

When macrophages perform their search-and-destroy missions, it is not simply up to apoptotic cells to flag down their destroyers. New results from Simon Brown (University of Edinburgh, Edinburgh, UK) and colleagues reveal that viable cells must actively avoid engulfment by phagocytes. A single ce

Journal: The Journal of Cell Biology, vol. 158, no. 3, 2002

Abstract

Barrier-to-autointegration factor (BAF) is a DNA-bridging protein, highly conserved in metazoans. BAF binds directly to LEM (LAP2, emerin, MAN1) domain nuclear membrane proteins, including LAP2 and emerin. We used site-directed mutagenesis and biochemical analysis to map functionally important re

Journal: The Journal of Cell Biology, vol. 158, no. 3, 2002