The Journal of Cell Biology - Volume 155, issue 5

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

The actin cytoskeleton is essential for cellular remodeling and many developmental and morphological processes. Twinfilin is a ubiquitous actin monomer–binding protein whose biological function has remained unclear. We discovered and cloned the Drosophila twinfilin homologue, and show that

Journal: The Journal of Cell Biology, vol. 155, no. 5, 2001

Abstract

We have shown previously that Ipl1 and Sli15 are required for chromosome segregation in Saccharomyces cerevisiae. Sli15 associates directly with the Ipl1 protein kinase and these two proteins colocalize to the mitotic spindle. We show here that Sli15 stimulates the in vitro, and likely in

Journal: The Journal of Cell Biology, vol. 155, no. 5, 2001