The Journal of Cell Biology - Volume 151, issue 2

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

c-src deletion in mice leads to osteopetrosis as a result of reduced bone resorption due to an alteration of the osteoclast. We report that deletion/reduction of Src expression enhances osteoblast differentiation and bone formation, contributing to the increase in bone mass. Bone histomorp

Journal: The Journal of Cell Biology, vol. 151, no. 2, 2000

Abstract

Mitochondrial morphology and function depend on MGM1, a Saccharomyces cerevisiae gene encoding a dynamin-like protein of the mitochondrial outer membrane. Here, we show that mitochondrial fragmentation and mitochondrial genome loss caused by lesions in MGM1 are suppressed by

Journal: The Journal of Cell Biology, vol. 151, no. 2, 2000