The Journal of Cell Biology - Volume 143, issue 3

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

α5-deficient mice die early in embryogenesis (Yang et al., 1993). To study the functions of α5 integrin later in mouse embryogenesis and during adult life we generated α5 −/−;+/+ chimeric mice. These animals contain α5-negative and positive cells randomly distributed. Analysis of the chimerism

Journal: The Journal of Cell Biology, vol. 143, no. 3, 1998

Abstract

The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that is defective in cystic fibrosis, and has also been closely associated with ATP permeability in cells. Using a Xenopus oocyte cRNA expression system, we have evaluated the molecular mechanisms that c

Journal: The Journal of Cell Biology, vol. 143, no. 3, 1998