The Journal of Cell Biology - Volume 141, issue 4

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Mitosis in human cells is initiated by the protein kinase Cdc2-cyclin B1, which is activated at the end of G2 by dephosphorylation of two inhibitory residues, Thr14 and Tyr15. The G2 arrest that occurs after DNA damage is due in part to stabilization of phosphorylation at these sites. We explo

Journal: The Journal of Cell Biology, vol. 141, no. 4, 1998