The Journal of Cell Biology - Volume 134, issue 6

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Electronic ISSN
1540-8140
Print ISSN
0021-9525

Abstract

Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration. Cells expressing CMF antisense mRNA fail to aggregate and do not transduce signals from the cAMP receptor. Signal transduction and aggrega

Journal: The Journal of Cell Biology, vol. 134, no. 6, 1996