PLoS ONE - Volume 6, issue 8

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Electronic ISSN
1932-6203

Abstract

Olfactory ensheathing cells (OECs) represent an interesting candidate for cell therapy and could be obtained from olfactory mucosa (OM-OECs) or olfactory bulbs (OB-OECs). Recent reports suggest that, depending on their origin, OECs display different functional properties. We show here the complem

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

Tumor-initiating cells (T-ICs) discovered in various tumors have been widely reported. However, T-IC populations in salivary gland tumors have yet to be elucidated. Using the established Pleomorphic Adenoma Gene-1 (Plag1) transgenic mouse model of a salivary gland tumor, we identified CD44hi

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

Penicillium dipodomyis is thought to be an exclusively asexual fungus associated with Kangaroo Rats, Dipodomys species, and is unique among Penicillium species in growing at 37°C but producing no known toxins. Lack of recombination within P. dipodomyis would result in

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

The affiliations for the 1st, 8th, 9th, and 10th authors were not indicated. The complete author list and affiliations are:

Junyan Feng(1,2), Lu Lu(1), Cong Hua(1), Ling Qin(1), Pingwei Zhao(1), Juan Wang(1), Ye Wang(1), Wanyu Li(2), Xiaodong Shi(2), Yanfang Jiang(1,2)

(1) Department

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

The ability to generate whole genome data is rapidly becoming commoditized. For example, a mammalian sized genome (∼3Gb) can now be sequenced using approximately ten lanes on an Illumina HiSeq 2000. Since lanes from different runs are often combined, verifying that each lane in a genome's build i

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

The small p97/VCP-interacting protein (SVIP) functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Here we show that overexpression of SVIP in HeLa cells leads to localization of p97/VCP at the plasma membrane, intracellular foci and juxtanuclear vacuo

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

One of the most striking aspects of animal groups is their remarkable variation in size, both within and between species. While a number of mechanistic models have been proposed to explain this variation, there are few comprehensive datasets against which these models have been tested. In particu

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

Background

In spite of a consistent protection against tuberculosis (TB) in children, Mycobacterium bovis Bacille Calmette-Guerin (BCG) fails to provide adequate protection against the disease in adults as well as against reactivation of latent infections or exogenous reinfections. It has b

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

Enterohemorrhagic Escherichia coli (EHEC) are food-borne pathogens that can cause serious infections ranging from diarrhea to hemorrhagic colitis (HC) and hemolytic-uremic syndrome (HUS). Translocation of Shiga-toxins (Stx) from the gut lumen to underlying tissues is a decisive step in the

Journal: PLoS ONE, vol. 6, no. 8, 2011

Abstract

Coniferous seed orchards require a long period from initial seed harvest to stable seed production. Differential reproductive success and asynchrony are among the main factors for orchard crops year-to-year variation in terms of parental gametic contribution and ultimately the genetic gain. It is

Journal: PLoS ONE, vol. 6, no. 8, 2011