PLoS ONE - Volume 6, issue 3

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Electronic ISSN
1932-6203

Abstract

Objectives

To determine the prevalence of type 2 diabetes mellitus, in three groups of Peruvian adults, using fasting glucose and glycosylated hemoglobin (A1C).

Methodology/Principal Findings

This study included adults from the PERU MIGRANT Study who had fasted ≥8 h. Fasting glucose ≥126 mg/d

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Background

The annotation of genomes from next-generation sequencing platforms needs to be rapid, high-throughput, and fully integrated and automated. Although a few Web-based annotation services have recently become available, they may

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Background

Public data integration may help overcome challenges in clinical implementation of microarray profiles. We integrated several ovarian cancer datasets to identify a reproducible predictor of survival.

Methodology/Principal Findings

Four microarray datasets from different institution

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

The coincidental evolution hypothesis predicts that traits connected to bacterial pathogenicity could be indirectly selected outside the host as a correlated response to abiotic environmental conditions or different biotic species interactions. To investigate this, an opportunistic bacterial path

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Human ESC and iPSC are an attractive source of cells of high quantity and purity to be used to elucidate early human development processes, for drug discovery, and in clinical cell therapy applications. To efficiently differentiate pluripotent cells into a pure population of hematopoietic progeni

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Acinetobacter calcoaceticus PHEA-2 utilizes phenol as its sole carbon and energy source and has a multi-component phenol hydroxylase-encoding gene operon (mphKLMNOP) for phenol degradation. Two additional genes, mphR and mphX, were found upstream and downstream of mphKLMNOP, respectively.

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Background and Aims

The association between hygiene and prevalence of autoimmune disease has been attributed in part to enteric helminth infection. A pilot study of experimental infection with the hookworm Necator americanus

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

We recently described the presence of large chromosomal segments resulting from independent horizontal gene transfer (HGT) events in the genome of Saccharomyces cerevisiae strains, mostly of wine origin. We report here evidence for the amplification of one of these segments, a 17 kb DNA se

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

Identifying the proximate and ultimate mechanisms of social behavior remains a major goal of behavioral biology. In particular, the complex social interactions mediating schooling behavior have long fascinated biologists, leading to theoretical and empirical investigations that have focused on sc

Journal: PLoS ONE, vol. 6, no. 3, 2011

Abstract

The intricate, hierarchical, highly reproducible, and exquisite biosilica structures formed by diatoms have generated great interest to understand biosilicification processes in nature. This curiosity is driven by the quest of researchers to understand nature's complexity, which might enable repr

Journal: PLoS ONE, vol. 6, no. 3, 2011