PLoS ONE - Volume 6, issue 11

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Electronic ISSN
1932-6203

Abstract

Background

Scale-up of highly active antiretroviral treatment therapy (HAART) programs in Rwanda has been highly successful but data on adherence is limited. We examined HAART adherence in a large cohort of HIV+ Rwandan women.

Methods

The Rwanda Women's Interassociation Study Assessment (RWIS

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Background

Kunitz-type venom peptides have been isolated from a wide variety of venomous animals. They usually have protease inhibitory activity or potassium channel blocking activity, which by virtue of the effects on predator animals are essential for the survival of venomous animals. However, n

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

The first author's name contains an error in the citation. The correct citation is: Truong HM, Kellogg TA, McFarland W, Louie B, Klausner JD, et al. (2011) Sentinel Surveillance of HIV-1 Transmitted Drug Resistance, Acute Infection and Recent Infection. PLoS ONE 6(10): e25281. doi:10.1371/journal

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Despite the explosion of interest in the genetic underpinnings of individual differences in pain sensitivity, conflicting findings have emerged for most of the identified “pain genes”. Perhaps the prime example of this inconsistency is represented by catechol-O-methyltransferase (COMT), as its su

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Tropical South America is rich in different groups of pollinators, but the biotic and abiotic factors determining the geographical distribution of their species richness are poorly understood. We analyzed the species richness of three groups of pollinators (bees and wasps, butterflies, hummingbir

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

DNA copy number variants (CNVs) have been reported in many human diseases including autism and schizophrenia. Primary Open Angle Glaucoma (POAG) is a complex adult-onset disorder characterized by progressive optic neuropathy and vision loss. Previous studies have identified rare CNVs in POAG; how

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Lung cancer is the leading cause of cancer-related death in the world. Non-small cell lung carcinomas (Non-SCLC) account for almost 80% of lung cancers, of which 40% were adenocarcinomas. For a better understanding of the molecular mechanisms behind the development and progression of lung cancer,

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Reproductive functions are regulated by the sophisticated coordination between the neuronal and endocrine systems and are sustained by a proper nutritional environment. Female reproductive function is vulnerable to effects from dietary restrictions, suggesting a transient adaptation that prioriti

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

The pathogenesis of neuromyelitis optica (NMO) involves binding of IgG autoantibodies (NMO-IgG) to aquaporin-4 (AQP4) on astrocytes in the central nervous system (CNS). We studied the in vivo processing in mice of a recombinant monoclonal human NMO-IgG that binds strongly to mouse AQP4. Fo

Journal: PLoS ONE, vol. 6, no. 11, 2011

Abstract

Secondary metabolite production is assumed to be costly and therefore the resource allocation to their production should be optimized with respect to primary biological functions such as growth or reproduction. Sponges are known to produce a great diversity of secondary metabolites with powerful

Journal: PLoS ONE, vol. 6, no. 11, 2011