PLoS ONE - Volume 4, issue 6

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Electronic ISSN
1932-6203

Abstract

Experimental protein-protein interaction (PPI) networks are increasingly being exploited in diverse ways for biological discovery. Accordingly, it is vital to discern their underlying natures by identifying and classifying the various types of deterministic (specific) and probabilistic (nonspecif

Journal: PLoS ONE, vol. 4, no. 6, 2009

Abstract

Background

Triterpene alcohols and acids are multifunctional compounds widely distributed throughout the plant kingdom that exhibit a variety of beneficial health properties, being synthetic analogs of oleanolic acid under clinical evaluation as anti-tumoral therapeutic agents. However, the antine

Journal: PLoS ONE, vol. 4, no. 6, 2009

Abstract

In addition to rods and cones, the human retina contains light-sensitive ganglion cells that express melanopsin, a photopigment with signal transduction mechanisms similar to that of invertebrate rhabdomeric photopigments (IRP). Like fly rhodopsins, melanopsin acts as a dual-state photosensitive

Journal: PLoS ONE, vol. 4, no. 6, 2009