Nucleic Acids Research - Volume 39, issue 10

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

Guanine-rich DNA sequences tend to form four-stranded G-quadruplex structures. Characteristic glycosidic conformational patterns along the G-strands, such as the 5′-syn-anti-syn-anti pattern observed with the Oxytricha nova telomeric G-quadruplexes, have been well documented. Howeve

Journal: Nucleic Acids Research, vol. 39, no. 10, 2011

Abstract

FACT complex is involved in elongation and ensures fidelity in the initiation step of transcription by RNA polymerase (pol) II. Histone variant H2A.Z is found in nucleosomes at the 5′-end of many genes. We report here H2A.Z-chaperone activity of the yeast FACT complex on the short, nucleosome-fre

Journal: Nucleic Acids Research, vol. 39, no. 10, 2011

Abstract

In eukaryotes, it is generally assumed that translation initiation occurs at the AUG codon closest to the messenger RNA 5′ cap. However, in certain cases, initiation can occur at codons differing from AUG by a single nucleotide, especially the codons CUG, UUG, GUG, ACG, AUA and AUU. While non-AUG

Journal: Nucleic Acids Research, vol. 39, no. 10, 2011

Abstract

A subscription to Nucleic Acids Research comprises 22 issues. All prices include postage, and for subscribers outside the UK delivery is by Standard Air. Nucleic Acids Research operates a model of continuous online publication, more details of which can be found at www.nar.oxfordjou

Journal: Nucleic Acids Research, vol. 39, no. 10, 2011