Nucleic Acids Research - Volume 37, issue 3

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

Topoisomerase II is an essential enzyme that is required for virtually every process that requires movement of DNA within the nucleus or the opening of the double helix. This enzyme helps to regulate DNA under- and overwinding and removes knots and tangles from the genetic material. In order to c

Journal: Nucleic Acids Research, vol. 37, no. 3, 2009

Abstract

Pre-mRNA splicing occurs in a large complex spliceosome. The steps of both spliceosome assembly and splicing reaction have been extensively analyzed, and many of the factors involved have been identified. However, the post-splicing intron turnover process, especially in vertebrates, remains to be

Journal: Nucleic Acids Research, vol. 37, no. 3, 2009