Nucleic Acids Research - Volume 36, issue 8

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

The Escherichia coli MelR protein is a transcription activator that autoregulates its own promoter by repressing transcription initiation. Optimal repression requires MelR binding to a site that overlaps the melR transcription start point and to upstream sites. In this work, we have

Journal: Nucleic Acids Research, vol. 36, no. 8, 2008

Abstract

DNA microarrays serve to monitor a wide range of molecular events, but emerging applications like measurements of weakly expressed genes or of proteins and their interaction patterns will require enhanced performance to improve specificity of detection and dynamic range. To further extend the uti

Journal: Nucleic Acids Research, vol. 36, no. 8, 2008