Nucleic Acids Research - Volume 36, issue 2

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

Negative co-factor 2 (NC2) is a conserved eukaryotic complex composed of two subunits, NC2α (Drap1) and NC2β (Dr1) that associate through a histone-fold motif. In this work, we generated mutants of NC2, characterized target genes for these mutants and studied the assembly of NC2 and general trans

Journal: Nucleic Acids Research, vol. 36, no. 2, 2008

Abstract

The nuclear RNA export factor (NXF) family proteins have been implicated in various aspects of post-transcriptional gene expression. This study shows that mouse NXF7 exhibits heterologous localization, i.e. NXF7 associates with translating ribosomes, stress granules (SGs) and processing bodies (P

Journal: Nucleic Acids Research, vol. 36, no. 2, 2008