Nucleic Acids Research - Volume 36, issue 15

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

HIV-1 reverse transcriptase (RT) is a primary target for anti-AIDS drugs. Structures of HIV-1 RT, usually determined at ∼2.5–3.0 Å resolution, are important for understanding enzyme function and mechanisms of drug resistance in addition to being helpful in the design of RT inhibitors. Despite hun

Journal: Nucleic Acids Research, vol. 36, no. 15, 2008