Nucleic Acids Research - Volume 36, issue 1

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

We have investigated the effects of duplex length, sequence, salt concentration and superhelical density on the conformation of DNA nanocircles containing up to 178 base pairs using atomistic molecular dynamics simulation. These calculations reveal that the partitioning of twist and writhe is gov

Journal: Nucleic Acids Research, vol. 36, no. 1, 2008