Nucleic Acids Research - Volume 33, issue 1

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Electronic ISSN
1362-4962
Print ISSN
0305-1048

Abstract

The tRNA 3′-processing endoribonuclease (tRNase Z or 3′ tRNase; EC 3.1.26.11) is an essential enzyme that removes the 3′ trailer from pre-tRNA. The long form (tRNase ZL) can cleave a target RNA in vitro at the site directed by an appropriate small-guide RNA (sgRNA). Here, we investigated w

Journal: Nucleic Acids Research, vol. 33, no. 1, 2005

Abstract

Using NMR methods, we have resolved the i-motif structures formed by d(AACCCC) and by d(CCCCAA), two versions of the DNA sequence repeated in the telomeric regions of the C-rich strand of tetrahymena chromosomes. Both oligonucleotides form fully symmetrical i-motif tetramers built by intercalatio

Journal: Nucleic Acids Research, vol. 33, no. 1, 2005