Molecular Vision - Volume 18, issue Preprint

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Electronic ISSN
1090-0535

Abstract

Purpose

To investigate the effects of topical FTY720 and cyclosporin A (CsA) on allogeneic corneal transplantation in mice.

Methods

A total of 75 BALB/c mice received corneal grafts from C57BL/6 donors. Recipients were treated with 0.1%, 0.3%, or 0.5% FTY720 ophthalmic gel or 1% CsA eye-drops

Journal: Molecular Vision, vol. 18, no. Preprint, 2012

Abstract

Purpose

The aim of this prospective study was to evaluate whether blending two kinds of biomaterials, chitosan and polycaprolactone (PCL), can be used as scaffold and carrier for growth and differentiation of corneal endothelial cells (CECs).

Methods

A transparent, biocompatible carrier with

Journal: Molecular Vision, vol. 18, no. Preprint, 2012

Abstract

Purpose

During mammalian eye development, the restriction of Wnt/β-catenin signaling at the junction of the neural retina and the retinal pigment epithelium in the peripheral eyecup is required for the development of the ciliary margin, a non-neural region of the eyecup that is the precursor of th

Journal: Molecular Vision, vol. 18, no. Preprint, 2012

Abstract

Purpose

Mutations in destrin (Dstn) cause corneal abnormalities in mice. A null mutation, Dstncorn1, results in corneal epithelial hyperproliferation, inflammation, and neovascularization in the A.BY background (A.BY Dstncorn1). Homozygosity for a point m

Journal: Molecular Vision, vol. 18, no. Preprint, 2012