Critical Care - Volume 7, issue 2

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Few actions taken by intensivists are as effective and inexpensive as application of positive end-expiratory pressure (PEEP). However, the use of this ventilatory modality is highly susceptible to fashions and trends that are rarely supported by scientific evidence. Prophylactic PEEP can be consi

Journal: Critical Care, vol. 7, no. 2, 2002



Drotrecogin alfa (activated; recombinant activated protein C) was shown to reduce 28-day all-cause mortality in patients with severe sepsis and to have an acceptable safety profile in 1690 patients studied in the F1K-MC-EVAD (PROWESS) trial. We analyzed all available data on the safet

Journal: Critical Care, vol. 7, no. 2, 2003