Critical Care - Volume 2, issue Suppl 1

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Electronic ISSN
1466-609X
Print ISSN
1364-8535

Abstract

This prospective placebo-controlled double-blind clinical study investigated the efficacy of the monoclonal anti-TNF antibody MAK 195F (Afelimomab) compared to placebo in patients suffering from severe sepsis and septic shock with highly elevated IL-6 levels. Patients were stratified at entry int

Journal: Critical Care, vol. 2, no. Suppl 1, 1998

Abstract

A fall in arterial oxygen partial pressure (PaO2) during nitrous oxide (N2O) elimination is a well known phenomenon denominated as diffusive hypoxia that is caused by the relatively fast N2O-elimination compared with the slower simultaneous N2-uptake. O

Journal: Critical Care, vol. 2, no. Suppl 1, 1998

Abstract

Inhaled nitric oxide (NO) reduces pulmonary hypertension in severe ARDS and improves arterial oxygenation by redistributing blood flow to areas with a normal ventilation/perfusion ratio [1]. As high peak inspiratory pressure (PIP) may contribute to pulmonary damage ventilatory strategies like hig

Journal: Critical Care, vol. 2, no. Suppl 1, 1998