British Journal of Cancer - Volume 95, issue 1

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

Pyrrolidinedithiocarbamate (PDTC) enhanced the activity of 5-fluorouracil (5-FU) in a colorectal cancer xenograft model. Pyrrolidinedithiocarbamate also reduced gastrointestinal toxicity associated with 5-FU therapy in large but not small bowel. We sought to clarify the basis of this differential

Journal: British Journal of Cancer, vol. 95, no. 1, 2006