British Journal of Cancer - Volume 86, issue 4

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

Microsatellite instability is present in over 80% of the hereditary non-polyposis colorectal carcinoma and about 15–20% of the sporadic cancer. Microsatellite instability is caused by the inactivation of the mismatch repair genes, such as primarily hMLH1, hMSH2. To study the mechani

Journal: British Journal of Cancer, vol. 86, no. 4, 2002