British Journal of Cancer - Volume 65, issue 3

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

Journal: British Journal of Cancer, vol. 65, no. 3, 1992

Abstract

Analogues of the neurotransmitter substance P (SP) can interact with neuropeptide receptors, and are reported to inhibit growth of small cell lung cancer cell lines (SCLC CLs). We found [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P (D-Phe5SP) significantly inhibited DNA synthesis by 10/10 human t

Journal: British Journal of Cancer, vol. 65, no. 3, 1992

Abstract

We have studied the pharmacokinetics of mitoxantrone in cancer patients. Two regimens were used: eight women (10 kinetics) received a 10 min i.v. infusion of 12 mg m-2 of mitoxantrone; seven women (seven kinetics) received high-dose mitoxantrone associated to high-dose alkylating agents and under

Journal: British Journal of Cancer, vol. 65, no. 3, 1992