British Journal of Cancer - Volume 64, issue 1

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

In the Edinburgh Randomised Breast Screening Project (EBSP) to December 1988 there were 500 cancers in the study population invited to screening and 340 cancers identified in the control population. The size and negative lymph node status characteristics of invasive cancers from the two populatio

Journal: British Journal of Cancer, vol. 64, no. 1, 1991

Abstract

Dose limiting systemic toxicity prevents sufficient exploitation of the steep dose response relationship of most anticancer agents. In our rat liver tumour model (the CC531 colorectal carcinoma), isolated liver perfusion allows administration of higher doses of mitomycin C than hepatic artery inf

Journal: British Journal of Cancer, vol. 64, no. 1, 1991

Abstract

Using an immunoradiometric assay, Cathepsin-D (Cath-D) concentrations were measured in the cytosol of 68 normal and neoplastic human ovarian tissues. Cath-D levels were higher in malignant tumours than in normal tissue samples (P less than 0.01) and benign tumours (P less than 0.01). In six out o

Journal: British Journal of Cancer, vol. 64, no. 1, 1991

Abstract

Damage arising from putative environmental sources has been found in the DNA of the gastric and colorectal mucosae of patients presenting with gastrointestinal disorders from the South Manchester area. O6-Methylguanine (O6-MeG) in the range 0.010- greater than 0.300 mu moles mole-1 adenine was he

Journal: British Journal of Cancer, vol. 64, no. 1, 1991