British Journal of Cancer - Volume 51, issue 3

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

We have investigated the modifying influence of 17-beta oestradiol (E2), on the cytotoxicity of methotrexate (MTX) towards two cell lines derived from human breast carcinoma. E2 (10(-7) M-10(-6) M) significantly reduced the antimetabolic effects of the drug towards an E2 non-responsive cell line,

Journal: British Journal of Cancer, vol. 51, no. 3, 1985