British Journal of Cancer - Volume 104, issue 12

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

Background:

This study compared the central nervous system (CNS) metastasis incidence between a temozolomide- and a dacarbazine-based regimen in untreated stage IV melanoma patients.

Methods:

A total of 150 patients were randomly assigned to receive either oral temozolomide (200 mg m−2</

Journal: British Journal of Cancer, vol. 104, no. 12, 2011