British Journal of Cancer - Volume 102, issue 5

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Electronic ISSN
1532-1827
Print ISSN
0007-0920

Abstract

Sir,

Phosphatase, homologue to tensin (PTEN), is a tumour suppressor protein that regulates the PI3K/AKT signalling pathway. Loss of PTEN expression results in overactivation of the Akt pathway and confers resistance to inhibitors of the epidermal growth factor receptor (EGFR). Recen

Journal: British Journal of Cancer, vol. 102, no. 5, 2010