Breast Cancer Research - Volume 6, issue 4

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Electronic ISSN
1465-542X
Print ISSN
1465-5411

Abstract

Introduction

The S100A7 (psoriasin) gene is highly expressed in ductal carcinoma in situ (DCIS) of the breast and can be downregulated in invasive carcinoma. Persistent S100A7 expression in invasive carcinoma is associated with a worse prognosis, and this effect may be mediated in part thro

Journal: Breast Cancer Research, vol. 6, no. 4, 2004

Abstract

Introduction

Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter of the TNF gene (-308 G>A and -238 G>A)

Journal: Breast Cancer Research, vol. 6, no. 4, 2004