Breast Cancer Research - Volume 6, issue 1

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Electronic ISSN
1465-542X
Print ISSN
1465-5411

Abstract

A considerable body of research indicates that mammary gland branching morphogenesis is dependent, in part, on the extracellular matrix (ECM), ECM-receptors, such as integrins and other ECM receptors, and ECM-degrading enzymes, including matrix metalloproteinases (MMPs) and their inhibitors, tiss

Journal: Breast Cancer Research, vol. 6, no. 1, 2003

Abstract

I read with interest the series of articles on 'Pre-invasive breast disease' in the September and November issues of Breast Cancer Research [1-9]. Although each of the articles is well written, the series raises several issues and in places is contradictory.

Loss of heterozygosity (L

Journal: Breast Cancer Research, vol. 6, no. 1, 2003

Abstract

Introduction

Many laboratories are currently evaluating the usefulness of determination of HER2, p53, and Ki67 proliferation indices using immunohistochemical techniques in cancer. Although the available studies suggest that these factors might indeed be helpful in making treatment decisions in ca

Journal: Breast Cancer Research, vol. 6, no. 1, 2003