BMC Medical Genetics - Volume 12, issue Preprint

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Electronic ISSN
1471-2350

Abstract

Background

The MAOA uVNTR polymorphism has been documented to affect the MAOA gene at the transcriptional level and is associated with aggressive impulsive behaviors, depression associated with suicide (depressed suicide), and major depressive disorder (MDD). We hypothesized that the uVNTR polymor

Journal: BMC Medical Genetics, vol. 12, no. Preprint, 2011

Abstract

Background

Temporomandibular disorder (TMD) is a multifactorial syndrome related to a critical period of human life. TMD has been associated with psychological dysfunctions, oxidative state and sexual dimorphism with coincidental occurrence along the pubertal development. In this work we study the

Journal: BMC Medical Genetics, vol. 12, no. Preprint, 2011

Abstract

Background

BCL-2 (B-cell leukemia/lymphoma 2) gene has been demonstrated to be associated with breast cancer development and a single nucleotide polymorphism (SNP; -938C > A) has been identified recently. To investigate whether this polymorphism functions as a modifier of breast cancer d

Journal: BMC Medical Genetics, vol. 12, no. Preprint, 2011

Abstract

Background

Low serum paraoxonase (PON) activity is associated with the risk of coronary artery disease, diabetes and systemic lupus erythematosus (SLE). Our prior studies have shown that the PON1/rs662 (p.Gln192Arg), PON1/rs854560 (p.Leu55Met), PON3/rs17884563 and PON3/

Journal: BMC Medical Genetics, vol. 12, no. Preprint, 2011