BMC Genomics - Volume 8, issue Preprint

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Electronic ISSN
1471-2164

Abstract

Background

Fast, efficiently growing animals have increased protein synthesis and/or reduced protein degradation relative to slow, inefficiently growing animals. Consequently, minimizing the energetic cost of protein turnover is a strategic goal for enhancing animal growth. Characterization of gen

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Protein domains are fundamental evolutionary units of protein architecture, composing proteins in a modular manner. Combinations of two or more, possibly non-adjacent, domains are thought to play specific functional roles within proteins. Indeed, while the number of potential co-occurri

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Oil palm is the second largest source of edible oil which contributes to approximately 20% of the world's production of oils and fats. In order to understand the molecular biology involved in in vitro propagation, flowering, efficient utilization of nitrogen sources and root dise

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

The evolutionary lineage leading to the teleost fish underwent a whole genome duplication termed FSGD or 3R in addition to two prior genome duplications that took place earlier during vertebrate evolution (termed 1R and 2R). Resulting from the FSGD, additional copies of genes are presen

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concordant with conserved RNA secondary structures have been discovered in the human g

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large numbers of DNA markers within large sample populations. Using pooled DNA on SNP m

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Lactation is an important aspect of mammalian biology and, amongst mammals, marsupials show one of the most complex lactation cycles. Marsupials, such as the tammar wallaby (Macropus eugenii) give birth to a relatively immature newborn and progressive changes in milk composition

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Identification of coordinately regulated genes according to the level of their expression during the time course of a process allows for discovering functional relationships among genes involved in the process.

Results

We present a single class classification method for the identif

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Long-lived strains of dwarf mice carry mutations that suppress growth hormone (GH) and insulin-like growth factor I (IGF-I) signaling. The downstream effects of these endocrine abnormalities, however, are not well understood and it is unclear how these processes interact with aging mech

Journal: BMC Genomics, vol. 8, no. Preprint, 2007

Abstract

Background

Cotton, as an allopolyploid species, contains homoeologous A and D subgenomes. The study of the homoeologous (duplicated) segments or chromosomes can facilitate insight into the evolutionary process of polyploidy and the development of genomic resources. Fluorescence in situ hybr

Journal: BMC Genomics, vol. 8, no. Preprint, 2007